Test2Learn^TM is an award-winning training approach where you can work with real genetic data to learn pharmacogenomics. You can experience personal genomics testing just like your patients or work with anonymous data.  Interactive exercises and real world cases increase the fidelity of education and make training fun.  Learn all about our learning outcomes by clicking on the logo to the left. 

TARGET AUDIENCE

All healthcare professionals
 

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SPECIFIC LEARNING MODULES

Home study Advances in Precision Medicine  and Pharmacogenomics The Pharmacist in Pharmacogenomics A Review of Genetics and Nomenclature Introduction to Medical Genetics Principles of Genetic and Genomic Testing Regulation and Reimbursement of Genetic and Genomic Testing Ethical Issues Associated with Genomic & PGx Testing Social Justice Issues Associated with Genomic & PGx Testing Consent and Communication of Genetic Test Results Pharmacogenetics Scientific Evidence to Clinical Guidelines Cardiovascular  Pharmacogenomics Psychiatric and Neurologic Pharmacogenomics Pharmacogenomics in Internal Medicine Pain Pharmacogenomics Hypersensitivity and Skin Reactions Oncology Pharmacogenomics Leading innovators – success stories: Identifying Opportunities and Implementing Pharmacogenomics (PGx) into Community Pharmacy Practice Leading innovators – success stories: A Pharmacogenomics-MTM model in Community pharmacy

Live program Population variability and PGx clinical decision making Leveraging PGx information resources Predicting PGx phenotypes using real genetic data Application to patient cases Communicating with patients and providers PGx implementation barriers Implementation models and transitions of care

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LEARNING OBJECTIVES

The pharmacist who completes the home-study and live components of this Pharmacogenomics Certificate Program should be able to:

• Demonstrate understanding of basic genetic/genomic concepts and nomenclature
• Describe advances in scientific knowledge and technology, which have led to innovations in personalized medicine
• Identify the role of behavioral, social and environmental factors (lifestyle, socioeconomic factors, pollutants, among others) to modify or influence genetics in the manifestation of disease.
• Compare and contrast different PGx study designs.
• Identify drug- and disease-associated genetic variations that facilitate development of prevention and treatment strategies and appreciate there are differences in testing methodologies and are aware of the need to explore these differences in drug literature evaluation
• Assess predisposition to disease and selection of drug treatment by using family history
• Describe the role of genetic factors in maintaining health and preventing disease
• Assess the difference between clinical diagnosis of disease and identification of genetic predisposition to disease (genetic variation is not strictly correlated with disease manifestation)
• Recognize that pharmacogenomic testing may also reveal certain genetic disease predispositions (e.g., the Apo E4 polymorphism)
• Demonstrate an understanding of how genetic variation in a large number of proteins influences pharmacokinetics and pharmacodynamics related to pharmacologic effect and drug response
• Use online resources to assign haplotypes and predicted drug response phenotypes from genetic data.
• Describe the influence (or lack thereof) of ethnicity in genetic polymorphisms and associations of polymorphisms with drug response
• Recognize the availability of evidence-based guidelines that synthesize information relevant to genomic/pharmacogenomic tests and selection of drug therapy (e.g. Clinical pharmacogenomics implementation consortium)
• Evaluate the availability of genetic testing under FDA, CLIA, and DTC regulations.
• Evaluate PGx test reports through group-based activities and role-playing to demonstrate the PGx knowledge/skill-based competencies
• Create a step-wise decision-making process for the integration of PGx with clinical variables known to impact PK/PD to make appropriate PGx-based recommendations for patients and populations.
• List drugs/clinical situations where PGx testing is likely to be most useful clinically
• Identify the potential physical and/or psychosocial benefits, limitations and risk of genomic/pharmacogenomic information for individuals, family members and communities, especially with genomic/pharmacogenomic tests that may relate to predisposition to disease
• Describe the increased liability that accompanies access to detailed genomic patient information and maintain confidentiality and security
• Define the cost, cost–effectiveness and reimbursement by insurers relevant to genomic or pharmacogenomic tests and test interpretation for patients and populations
• Identify the need to refer a patient to a genetic specialist or genetic counselor
• Describe proper documentation of test results in electronic patient record
• Adopt a culturally sensitive and ethical approach to patient counseling regarding PGx test results
• Demonstrate patient and provider communication about PGx testing and test results and counseling through group-based activities and role-playing
• Evaluate about different business models to integrate PGx in various practice sites
• Discuss different strategies to engage with local practitioners to optimize the delivery of PGx services prior to implementation
• Demonstrate proficiency in different types of sample collection practices for PGx testing, review of safety procedures for handling biospecimens and proper mailing
   

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DISCLAIMER STATEMENT

The information presented at this activity represents the views and opinions of the individual presenters, and does not constitute the opinion or endorsement of, or promotion by, the UPMC Center for Continuing Education in the Health Sciences, UPMC / University of Pittsburgh Medical Center or Affiliates and University of Pittsburgh School of Medicine.  Reasonable efforts have been taken intending for educational subject matter to be presented in a balanced, unbiased fashion and in compliance with regulatory requirements. However, each program attendee must always use his/her own personal and professional judgment when considering further application of this information, particularly as it may relate to patient diagnostic or treatment decisions including, without limitation, FDA-approved uses and any off-label uses.

	Philip Empey, PharmD, PhD,  FCCP Associate Director, Institute of Precision Medicine; Associate Professor, Pharmacy and Therapeutics, University of Pittsburgh School of Pharmacy Faculty profile
	James Coons, PharmD, FCCP, FACC, BCCP PGY2 Cardiology Residency Program Director; Professor, Pharmacy and Therapeutics, School of Pharmacy, University of Pittsburgh Faculty profile
	Lucas Berenbrok, PharmD, MS, BCACP, TTS Associate Professor, Pharmacy and Therapeutics, School of Pharmacy, University of Pittsburgh Faculty profile

Conflict of Interest Disclosure

No planners, members of the planning committee, speakers, presenters, authors, content reviewers and/or anyone else in a position to control the content of this education activity have relevant financial relationships to disclose.
 

HOME STUDY

• Self-paced, online (to be completed in advance of the live program date)
  
  

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FACULTY-LED, LIVE PROGRAM: Tuesday, July 25, 2023

(All times eastern and conducted over Zoom)

7:45 am	Program registration
8:00 am - 12:00 pm	Certificate training program morning session
12:00 pm	Break for lunch
1:00 pm - 4:30 pm	Certificate training program afternoon session

ACCREDITATION

In support of improving patient care, the University of Pittsburgh is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME) and the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Physician (CME)

The University of Pittsburgh designates this enduring material activity for a maximum of 1.0 AMA PRA Category 1 Credit[s]™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Pharmacy (CPE)

This knowledge-based activity provides 1.0 contact hours of continuing pharmacy education credit.

Other health care professionals will receive a certificate of attendance confirming the number of contact hours commensurate with the extent of participation in this activity.  

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HOW TO OBTAIN CONTINUING EDUCATION

Continuing education is available for the above learner groups. Learners must complete the full program (all modules, attain grades of 80% or higher on assessments, and participate in the live session) as well as submit necessary information to for submission of credit (e.g. profile information and evaluations) to receive continuing education credit. Partial credit will not be awarded.

TARGET AUDIENCE

All healthcare professionals

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LEARNING OBJECTIVES

Upon completion of this activity, participants should be able to:

• Review the nomenclature for PGx
  
• Review available evidence sources for pharmacogenomic recommendations. 
• Describe how Clinical Pharmacogenetic Implementation Consortium (CPIC) guidelines are developed, the components of a CPIC guideline and how CPIC guidelines can be used by clinicians to make specific prescribing decisions for patient care. 
• Retrieve the levels of evidence for gene/drug pairs.
• Integrate information from US Food and Drug Administration (FDA), CPIC, and PharmGKB into pharmacogenomic clinical decision making.

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DISCLAIMER STATEMENT

The information presented at this activity represents the views and opinions of the individual presenters, and does not constitute the opinion or endorsement of, or promotion by, the UPMC Center for Continuing Education in the Health Sciences, UPMC / University of Pittsburgh Medical Center or Affiliates and University of Pittsburgh School of Medicine.  Reasonable efforts have been taken intending for educational subject matter to be presented in a balanced, unbiased fashion and in compliance with regulatory requirements. However, each program attendee must always use his/her own personal and professional judgment when considering further application of this information, particularly as it may relate to patient diagnostic or treatment decisions including, without limitation, FDA-approved uses and any off-label uses.

Released 03/01/2023,  Expires 03/01/2026

Planning Committee for the ISCC-PEG Pharmacogenomics Learning Series:

• Philip Empey, PharmD, PhD, FCCP (University of Pittsburgh School of Pharmacy)
• Andrew Monte, MD, PhD (University of Colorado)
  
• Trina Walker, DNP, APRN, FNP-C (Creighton University)
• Nguyen Park, MS, PA-C (National Human Genome Research Institute)
• Jeneva Gularte-Rinaldo, PhD, RN (Samuel Merritt University)

Course Director

Spoorthy Reddy University of Colorado

Additional Content Reviewers

• Christina Aquilante, PharmD, Director of Pharmacogenomics for the Colorado Center for Personalized Medicine; Professor, Department of Pharmaceutical Sciences; University of Colorado
• Kathy Giacomini, PhD, Dean and Professor, School of Pharmacy; Co-Director UCSF-Stanford Center of Excellence in Regulatory Sciences and Innovation; University of California, San Francisco 
  

ACCREDITATION

In support of improving patient care, the University of Pittsburgh is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME) and the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Physician (CME)

The University of Pittsburgh designates this enduring material activity for a maximum of 1.0 AMA PRA Category 1 Credit[s]™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nursing (CNE)

The maximum number of hours awarded for this Continuing Nursing Education activity is 1.0 contact hours.

Physician Assistant (AAPA)

The University of Pittsburgh has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 1.0 AAPA Category 1 CME credits. PAs should only claim credit commensurate with the extent of their participation.  

Pharmacy (CPE)

This knowledge-based activity provides 1.0 contact hours of continuing pharmacy education credit.

Other health care professionals will receive a certificate of attendance confirming the number of contact hours commensurate with the extent of participation in this activity.

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HOW TO OBTAIN CONTINUING EDUCATION

Continuing education is available for the above learner groups for a small processing fee.   Please register for the course using the 'Pay Now' button below.  Once you complete the course, the "If requesting continuing education (paid users only)" instructions will unlock automatically with further instructions.

TARGET AUDIENCE

All healthcare professionals

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LEARNING OBJECTIVES

Upon completion of this activity, participants should be able to:

• Review available evidence sources for pharmacogenomic recommendations. 
  
• Describe the components of a CPIC guideline and how CPIC guidelines can be used by clinicians to make specific prescribing decisions for patient care. 
• Explain how evidence-based guidelines are developed by CPIC.
• Retrieve the levels of evidence for gene/drug pairs.
• Integrate information from FDA, CPIC, and PharmGKB into pharmacogenomic clinical decision making.
  

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DISCLAIMER STATEMENT

The information presented at this activity represents the views and opinions of the individual presenters, and does not constitute the opinion or endorsement of, or promotion by, the UPMC Center for Continuing Education in the Health Sciences, UPMC / University of Pittsburgh Medical Center or Affiliates and University of Pittsburgh School of Medicine.  Reasonable efforts have been taken intending for educational subject matter to be presented in a balanced, unbiased fashion and in compliance with regulatory requirements. However, each program attendee must always use his/her own personal and professional judgment when considering further application of this information, particularly as it may relate to patient diagnostic or treatment decisions including, without limitation, FDA-approved uses and any off-label uses.

Released 04/24/2023,  Expires 04/24/2026

Planning Committee for the ISCC-PEG Pharmacogenomics Learning Series:

• Philip Empey, PharmD, PhD, FCCP (University of Pittsburgh School of Pharmacy)
• Andrew Monte, MD, PhD (University of Colorado)
  
• Trina Walker, DNP, APRN, FNP-C (Creighton University)
• Nguyen Park, MS, PA-C (National Human Genome Research Institute)
• Jeneva Gularte-Rinaldo, PhD, RN (Samuel Merritt University)

Course Directors

	Philip Empey, PharmD, PhD Associate Professor and Director, Pharmacogenomics Center of Excellence University of Pittsburgh School of Pharmacy
	Benjamin Brown American Society of Pharmacovigilance

Additional Content Reviewers

• Kelly Caudle, PharmD, PhD, Director, Clinical Pharmacogenetics Implementation Consortium
• Wendy Rubinstein, MD, PhD, Director, Personalized Medicine, Food & Drug Administration (Questions 1 and 3 only).  The review does not constitute an endorsement by FDA or any of its employees
  

ACCREDITATION

In support of improving patient care, the University of Pittsburgh is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME) and the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Physician (CME)

The University of Pittsburgh designates this enduring material activity for a maximum of 1.0 AMA PRA Category 1 Credit[s]™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nursing (CNE)

The maximum number of hours awarded for this Continuing Nursing Education activity is 1.0 contact hours.

Physician Assistant (AAPA)

The University of Pittsburgh has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 1.0 AAPA Category 1 CME credits. PAs should only claim credit commensurate with the extent of their participation.  

Pharmacy (CPE)

This knowledge-based activity provides 1.0 contact hours of continuing pharmacy education credit.

Other health care professionals will receive a certificate of attendance confirming the number of contact hours commensurate with the extent of participation in this activity.

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HOW TO OBTAIN CONTINUING EDUCATION

Continuing education is available for the above learner groups for a small processing fee.   Please register for the course using the 'Pay Now' button below.  Once you complete the course, the "If requesting continuing education (paid users only)" instructions will unlock automatically with further instructions.